The world No. 3 spent the majority of his career living in the shadow of his good friend but has enjoyed being the top player in his country over the past few seasons, with Federer enduring a barren spell in terms of success at the majors. Lopez just won Queen's and is always a threat on grass, so that potential fourth round against Djokovic could be a tough obstacle for the Serb.
The draw for Wimbledon 2017 was made at the All England Club on Friday.
"I would know more about it, I think, if it had been a really significant injury".
"So especially on grass with his serve, which is maybe the best in the game, he can beat anybody on any day".
Nobody, of course, has done it before as often as the 18-time grand slam champion Federer himself, who admitted it "hurt" to miss out on competing on the sapping clay of the French Open when he knew he was fit and raring to go.
Yet the 35-year-old is too old a hand to insist that this is going to be a four-horse race.
The Swiss, favourite to win a record eighth title, opens against Alexandr Dolgopolov. This is clearly not an ideal preparation. "I had success without feeling myself in great shape", he added.
Spithill skippers Oracle to 1st win in America's Cup
Spithill blinked first, making the turn before Burling and slowly inching closer to the Kiwis as they headed towards gate two. He was keen to heap pressure on the challengers heading into two further races on Monday (NZT).
The "big four" have dominated Wimbledon to a greater extent than any other grand slam, hogging the title between them since Federer's first triumph in 2003.
World number one and top seed Murray who is looking to win his third title in London was drawn in the top half with Rafael Nadal.
There, he is due to meet Novak Djokovic.
As for French Open victor Nadal, he pulled out of his scheduled warm-up event at Queen's, choosing instead to practise on grass at home in Majorca.
The seedings, released by the All England Club on Wednesday, have defending champion Andy Murray number one in the men's singles with Germany's Angelique Kerber the women's top seed. "It's that simple. It's the same for Novak and the same for Rafa", reckoned Federer.
He pulled out of his scheduled warm-up event at Queen's, choosing instead to practise on grass at home in Majorca, and is cautiously optimistic about his prospects. "I am playing well since the beginning of the season, so let's see".
All in all he could certainly have had more hard draws for his defence.
"For me, if he can get through that first round and feel better afterwards, absolutely he should play".